Giving the right tug for migration: Cadherins in tissue movements

被引：26

作者：

Becker, Sarah F. ^{[1
]}

Langhe, Rahul ^{[1
]}

Huang, Chaolie ^{[1
]}

Wedlich, Doris ^{[1
]}

Kashef, Jubin ^{[1
]}

机构：

[1] KIT Campus S, Inst Zool, Dept Cell & Dev Biol, D-76131 Karlsruhe, Germany

来源：

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 2012年 / 524卷 / 01期

关键词：

Neural crest migration; Gastrulation; Convergent extension; Epiboly; Optic/otic vesicle formation; PCP signaling; NEURAL CREST MIGRATION; BREAST-CANCER CELLS; XENOPUS PARAXIAL PROTOCADHERIN; CANDIDATE TUMOR-SUPPRESSOR; GLASS-ONION LOCUS; N-CADHERIN; BETA-CATENIN; CONVERGENT EXTENSION; VE-CADHERIN; ALPHA-CATENIN;

D O I：

10.1016/j.abb.2012.02.013

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

Dynamically regulated cell-cell adhesion is crucial for morphogenesis during embryonic development and tumor progression. The cadherins as calcium-dependent cell-cell adhesion proteins represent key molecules in these tissue movements. How cadherins serve in maintaining tissue cohesion during migration, facilitate cell-cell communication and promote signaling will be summarized in this review. (C) 2012 Elsevier Inc. All rights reserved.

引用

页码：30 / 42

页数：13

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