The first isolation of an alkoxy-N,N-dialkylaminodifluorosulfane from the reaction of an alcohol and DAST:: an efficient synthesis of (2S,3R,6S)-3-fluoro-2,6-diaminopimelic acid

被引：36

作者：

Sutherland, A ^{[1
]}

Vederas, JC ^{[1
]}

机构：

[1] Univ Alberta, Dept Chem, Edmonton, AB T6G 2G2, Canada

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 17期

关键词：

D O I：

10.1039/a904821i

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

During improvement of the synthesis of (2S,3R,6S)-3-fluoro-2,6-diaminopimelic acid 3, a potent inhibitor of DAP epimerase, a stable alkoxy-N,N-dialkylaminodifluorosulfane 9 was isolated from the reaction of alcohol 6 with DAST.

引用

页码：1739 / 1740

页数：2

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