Poly(norepinephrine): Ultrasmooth Material-Independent Surface Chemistry and Nanodepot for Nitric Oxide

被引：269

作者：

Hong, Seonki ^{[1
]}

Kim, Jihoon ^{[2
,3
]}

Na, Yun Suk ^{[1
]}

Park, Junghong ^{[2
,3
]}

Kim, Sunjin ^{[1
]}

Singha, Kaushik ^{[2
,3
]}

Im, Gun-Il ^{[4
]}

Han, Dong-Keun ^{[5
]}

Kim, Won Jong ^{[2
,3
]}

Lee, Haeshin ^{[1
]}

机构：

[1] Korea Adv Inst Sci & Technol, Dept Chem, Taejon 305701, South Korea

[2] Pohang Univ Sci & Technol POSTECH, Inst Basic Sci, Ctr Self Assembly & Complex, Pohang 790784, South Korea

[3] Pohang Univ Sci & Technol POSTECH, Dept Chem, Pohang 790784, South Korea

[4] Dongguk Univ, Ilsan Hosp, Dept Orthopaed, Goyang 411773, South Korea

[5] Korea Inst Sci & Technol, Biomat Res Ctr, Seoul 130650, South Korea

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 35期

关键词：

drug delivery; bioinspired chemistry; nitric oxide; polymers; surface chemistry; DOPAMINE FUNCTIONALIZATION; CELL-ADHESION; FILMS; NORADRENALINE; RELEASE; DRIVEN; ROUTE; LAYER; GOLD;

D O I：

10.1002/anie.201301646

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Capture and release: The material-independent surface chemistry of a poly(norepinephrine) (pNE) which exhibits perfect smoothness at the nanometer scale is controlled by 3,4-dihydroxybenzaldehyde-norepinephrine (DHBA-NE) conjugates. The pNE layer containing DHBA-NE serves to store and release small therapeutics such as nitric oxide. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：9187 / 9191

页数：5

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