The effects of hypertonic saline in healthy and diseased animals

被引：8

作者：

Cambier, C

Ratz, V

Rollin, F

Frans, A

Clerbaux, T

Gustin, P

机构：

[1] UNIV LIEGE, FAC VET MED, DEPT PHARMACOL & TOXICOL, B-4000 LIEGE, BELGIUM

[2] UNIV LIEGE, FAC VET MED, DEPT LARGE ANIM INTERNAL MED, B-4000 LIEGE, BELGIUM

[3] UNIV VET MED, DEPT PHARMACOL & TOXICOL, H-1400 BUDAPEST, HUNGARY

[4] UNIV CATHOLIQUE LOUVAIN, CLIN UNIV ST LUC, DIV PNEUMOL & CARDIOL, DEPT INTERNAL MED, B-1200 BRUSSELS, BELGIUM

来源：

VETERINARY RESEARCH COMMUNICATIONS | 1997年 / 21卷 / 05期

关键词：

alkalosis; endotoxin; haemorrhage; hypertonic saline; hypochloraemia; shock;

D O I：

10.1023/A:1005804102715

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

In this review, the pharmacological effects of administering hypertonic solutions to both healthy animals and during experimentally induced diseases are considered with a view to understanding the mechanisms behind the possible clinical efficacy of such treatment. The review focuses successively on haemorrhagic shock, endotoxic shock and hypokalaemic metabolic alkalosis. How hypertonic saline solutions affect oxygen transport by haemoglobin is also considered.

引用

页码：303 / 316

页数：14

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BROWN JM, 1990, J TRAUMA, V30, P646

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