Synthesis of carbocycles via intramolecular conjugate additions: Another solution to the terpenoid side chain stereochemistry problem

被引：21

作者：

Guevel, AC ^{[1
]}

Hart, DJ ^{[1
]}

机构：

[1] OHIO STATE UNIV,DEPT CHEM,COLUMBUS,OH 43210

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1996年 / 61卷 / 02期

关键词：

D O I：

10.1021/jo951531m

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Intramolecular conjugate additions of keto esters 7-11, mediated by pyrrolidine-acetic acid, provide perhydroindans or bicyclo[6.3.0]undecanes with high levels of diastereoselectivity at the acyclic stereogenic center. Levels of acyclic diastereoselection depend on starting unsaturated ester olefin geometry.

引用

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页码：465 / 472

页数：8

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