Enantioselective monoreduction of 2-alkyl-1,3-diketones mediated by chiral ruthenium catalysts. Dynamic kinetic resolution

被引：62

作者：

Eustache, F ^{[1
]}

Dalko, PI ^{[1
]}

Cossy, J ^{[1
]}

机构：

[1] Ecole Super Phys & Chim Ind Ville Paris, CNRS, Chim Organ Lab, F-75231 Paris 05, France

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 08期

关键词：

D O I：

10.1021/ol025527q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHIC] The reduction of 2-alkyl-1,3-diketones using (R,R)- or (S,S)-RuCl[N-(tosyl)-1,2-diphenylethylenediamine](p-cymene) in the presence of formic acid and triethylamine affords syn-2-alkyl-3-hydroxy ketones as the major products with high enantioselectivity.

引用

页码：1263 / 1265

页数：3

共 21 条

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