Tripropeptins, novel antimicrobial agents produced by Lysobacter sp.: I.: Taxonomy, isolation and biological activities

被引：71

作者：

Hashizume, H ^{[1
]}

Igarashi, M ^{[1
]}

Hattori, S ^{[1
]}

Hori, M ^{[1
]}

Hamada, M ^{[1
]}

Takeuchi, T ^{[1
]}

机构：

[1] Inst Microbial Chem, Shinagawa Ku, Tokyo 1410021, Japan

来源：

JOURNAL OF ANTIBIOTICS | 2001年 / 54卷 / 12期

关键词：

D O I：

10.7164/antibiotics.54.1054

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Peptide antibiotics tripropeptins A, B, C, D and Z were isolated from cultured cells and broth of Lysobacter sp. The differences among these components are in the lengths of the alkyl side chain. Tripropeptins are active against Gram-positive bacteria including MRSA in vitro. Bactericidal activity of tripropeptin C disappeared in the simultaneous presence of chloramphenicol, a bacteriostatic agent.

引用

页码：1054 / 1059

页数：6

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