Binding affinities of gallotannin analogs with bovine serum albumin: ramifications for polyphenol-protein molecular recognition

被引：45

作者：

Feldman, KS ^{[1
]}

Sambandam, A ^{[1
]}

Lemon, ST ^{[1
]}

Nicewonger, RB ^{[1
]}

Long, GS ^{[1
]}

Battaglia, DF ^{[1
]}

Ensel, SM ^{[1
]}

Laci, MA ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA

来源：

PHYTOCHEMISTRY | 1999年 / 51卷 / 07期

关键词：

gallotannin; equilibrium dialysis; protein binding;

D O I：

10.1016/S0031-9422(99)00144-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A series of gallotannin analogs were prepared by chemical synthesis, and their affinity for the test-case protein bovine serum albumin was measured by equilibrium dialysis. The structure/activity data obtained suggest that the naturally occurring gallotannins, in fact, do not represent the optimal protein recognition agents amongst polyphenolated templates. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：867 / 872

页数：6

共 20 条

[1] IRON (III) COMPLEXES WITH PHENOLS .4. ACID CONSTANTS OF SOME POLYPHENOLS [J].

ACKERMANN, G ;

HESSE, D ;

VOLLAND, P .

ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE, 1970, 377 (01) :92-+

[2] INTERACTIONS OF CONDENSED TANNINS WITH SELECTED PROTEINS [J].

ASQUITH, TN ;

BUTLER, LG .

PHYTOCHEMISTRY, 1986, 25 (07) :1591-1593

[3] HEMANALYSIS OF TANNINS - CONCEPT OF RELATIVE ASTRINGENCY [J].

BATESMIT.EC .

PHYTOCHEMISTRY, 1973, 12 (04) :907-912

[4] PLANT POLYPHENOLS - SECONDARY METABOLISM AND CHEMICAL DEFENSE - SOME OBSERVATIONS [J].

BEART, JE ;

LILLEY, TH ;

HASLAM, E .

PHYTOCHEMISTRY, 1985, 24 (01) :33-38

[5]

BERNAYS EA, 1989, ADV ECOL RES, P262

[6] INTERACTION OF PROTEINS WITH SORGHUM TANNIN - MECHANISM, SPECIFICITY AND SIGNIFICANCE [J].

BUTLER, LG ;

RIEDL, DJ ;

LEBRYK, DG ;

BLYTT, HJ .

JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 1984, 61 (05) :916-920

[7]

Feeny PP, 1976, RECENT ADV PHYTOCHEM, V10, P1, DOI DOI 10.1007/978-1-4684-2646-5_1

[8] ELLAGITANNIN CHEMISTRY - THE FIRST TOTAL CHEMICAL SYNTHESIS OF AN ELLAGITANNIN NATURAL PRODUCT, TELLIMAGRANDIN I [J].

FELDMAN, KS ;

ENSEL, SM ;

MINARD, RD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (05) :1742-1745

[9]

HAGERMAN AE, 1981, J BIOL CHEM, V256, P4494

[10] SPECIFICITY OF TANNIN-BINDING SALIVARY PROTEINS RELATIVE TO DIET SELECTION BY MAMMALS [J].

HAGERMAN, AE ;

ROBBINS, CT .

CANADIAN JOURNAL OF ZOOLOGY, 1993, 71 (03) :628-633

← 1 2 →