Adenosine and neuronal plasticity

被引：80

作者：

deMendonca, A ^{[1
]}

Ribeiro, JA ^{[1
]}

机构：

[1] HOSP SANTA MARIA,CTR ESTUDOS EGAS MONIZ,P-1600 LISBON,PORTUGAL

来源：

LIFE SCIENCES | 1996年 / 60卷 / 4-5期

关键词：

adenosine; paired-pulse facilitation; posttetanic depression; long-term potentiation; long-term depression; depotentiation; hippocampus; synaptic plasticity; NMDA;

D O I：

10.1016/S0024-3205(96)00544-9

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Adenosine is considered an important neuromodulator of the nervous system acting at pre-, post- and non-synaptic levels. In the present review we describe how adenosine modifies paired-pulse facilitation (PPF), posttetanic depression (PTD), long-term potentiation (LTP), long-term depression (LTD) and depotentiation at the hippocampus, and therefore how this nucleoside modulates synaptic plasticity.

引用

页码：245 / 251

页数：7

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