A global evaluation of voriconazole activity tested against recent clinical isolates of Candida spp.

被引:27
作者
Diekema, Daniel J. [1 ,2 ]
Messer, Shawn A. [2 ]
Hollis, Richard J. [2 ]
Boyken, Linda [2 ]
Tendolkar, Shailesh [2 ]
Kroeger, Jennifer [2 ]
Jones, Ronald N. [4 ]
Pfaller, Michael A. [2 ,3 ]
机构
[1] Univ Iowa, Carver Coll Med, Dept Internal Med, Iowa City, IA 52242 USA
[2] Univ Iowa, Carver Coll Med, Dept Pathol, Iowa City, IA 52242 USA
[3] Univ Iowa, Carver Coll Med, Dept Epidemiol, Iowa City, IA 52242 USA
[4] Jones Microbiol Inst, N Liberty, IA 52317 USA
关键词
Voriconazole; Surveillance; Candida; IN-VITRO ACTIVITIES; ANTIFUNGAL SUSCEPTIBILITY; RECEIVING VORICONAZOLE; FUNGAL-INFECTIONS; UNITED-STATES; SURVEILLANCE; FLUCONAZOLE; GLABRATA; FUNGEMIA; SPP;
D O I
10.1016/j.diagmicrobio.2008.11.001
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Voriconazole susceptibility testing was performed on 7191 Candida spp. from 78 centers worldwide between 2004 and 2007. Voriconazole was very active in vitro (MIC50/MIC90, 0.008/0.25 mu g/mL; 98% susceptible). In comparison to 5866 Candida spp. isolates collected during global Surveillance from 1997 to 2001, there were no changes in voriconazole mean MIC or MIC distribution. (c) 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码:233 / 236
页数:4
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