Separation of racemic 2,4-dinitrophenyl amino acids on carboxymethyl-β-cyclodextrin coated zirconia in RPLC

被引：27

作者：

Park, SY

Park, JK

Park, JH ^{[1
]}

McNeff, CV

Carr, PW

机构：

[1] Yeungnam Univ, Dept Chem, Kyongsan 712749, South Korea

[2] Zirchrom Separat Inc, Anoka, MN 55303 USA

[3] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA

来源：

MICROCHEMICAL JOURNAL | 2001年 / 70卷 / 03期

关键词：

carboxymethyl-beta-cyclodextrin-coated zirconia; chiral stationary phase; LC; RPLC separation; racemic DNP-amino acids;

D O I：

10.1016/S0026-265X(01)00129-1

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

We report preparation and use of carboxymethyl-beta -cyclodextrin-coated zirconia as a chiral stationary phase (CSP) for separation of enantiomers of 2,4-dinitrophenyl (DNP) amino acids in reversed-phase high performance liquid chromatography. The CSP showed good enantioselectivity for some of the amino acids studied. Effects of pH and amount of methanol in mobile phases on retention and enantioselectivity for the analytes were examined. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：179 / 185

页数：7

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