Imaging in knee osteoarthritis

被引：50

作者：

Oo, Win M. ^{[1
,2
]}

Linklater, James M. ^{[3
]}

Hunter, David J. ^{[1
,2
]}

机构：

[1] Univ Sydney, Royal North Shore Hosp, Dept Rheumatol, Clin Adm 7C,POB 2065, Sydney, NSW, Australia

[2] Univ Sydney, Kolling Inst, Inst Bone & Joint Res, Clin Adm 7C,POB 2065, Sydney, NSW, Australia

[3] Castlereagh Sports Imaging Ctr, Dept Musculoskeletal Imaging, St Leonards, NSW, Australia

来源：

CURRENT OPINION IN RHEUMATOLOGY | 2017年 / 29卷 / 01期

基金：

英国医学研究理事会;

关键词：

MRI; osteoarthritis; plain radiography; ultrasound; x-rays; CARTILAGE VOLUME LOSS; BONE-MARROW LESIONS; ANTERIOR CRUCIATE LIGAMENT; STRUCTURAL JOINT DAMAGE; FAT PAD VOLUME; RADIOGRAPHIC OSTEOARTHRITIS; MENISCAL EXTRUSION; CLINICAL-TRIAL; OLDER-ADULTS; MULTICENTER OSTEOARTHRITIS;

D O I：

10.1097/BOR.0000000000000350

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Purpose of reviewOsteoarthritis is the most prevalent and disabling disease still necessitating research in pathogenic mechanisms, predictors of disease progression and responsive techniques to detect the slow structural changes within a short time frame. In this scenario, imaging modalities are essential. With recent advancements in technology and availability of large longitudinal datasets, tremendous advances are occurring. The present review discusses and summarizes recent original publications in this area.Recent findingsMRI has been the most popular modality used to evaluate the different roles of structural disorders in incident knee osteoarthritis, to compare predictability of individual features of semiquantitative scores for knee replacement and to formulate different disease progression models. More ultrasound studies have been published, including the proposed semiquantitative scoring system by the Outcome Measures in Rheumatoid Arthritis Clinical Trial group.SummaryAs more advanced emerging technologies are developed in imaging, there are great opportunities to formulate new incident and prediction osteoarthritis models and to discover tissue-targeted disease-modifying drugs.

引用

页码：86 / 95

页数：10

共 72 条

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