Statins: the next step in adjuvant therapy for sepsis?

被引：21

作者：

Mekontso-Dessap, A

Brun-Buisson, C

机构：

[1] Hop Henri Mondor, Serv Reanimat Med, Hop Paris, F-94000 Creteil, France

[2] Univ Paris 12, F-94000 Creteil, France

来源：

INTENSIVE CARE MEDICINE | 2006年 / 32卷 / 01期

关键词：

statin; sepsis; HMG-CoA; adjuvant therapy;

D O I：

10.1007/s00134-005-2860-5

中图分类号：

R4 [临床医学];

学科分类号：

1002 [临床医学]; 100602 [中西医结合临床];

摘要：

引用

收藏

页码：11 / 14

页数：4

相关论文

共 25 条

[1]

Prior statin therapy is associated with a decreased rate of severe sepsis [J].

Almog, Y ;

Shefer, A ;

Novack, V ;

Maimon, N ;

Barski, L ;

Eizinger, M ;

Friger, M ;

Zeller, L ;

Danon, A .

CIRCULATION, 2004, 110 (07) :880-885

[2]

Ando H, 2000, J PHARMACOL EXP THER, V294, P1043

[3]

Arnaud C, 2005, ARCH MAL COEUR VAISS, V98, P661

[4]

Intensive versus moderate lipid lowering with statins after acute coronary syndromes [J].

Cannon, CP ;

Braunwald, E ;

McCabe, CH ;

Rader, DJ ;

Rouleau, JL ;

Belder, R ;

Joyal, SV ;

Hill, KA ;

Pfeffer, MA ;

Skene, AM .

NEW ENGLAND JOURNAL OF MEDICINE, 2004, 350 (15) :1495-1504

[5]

HMG-CoA reductase inhibitors for lowering elevated levels of C-reactive protein [J].

Chan, KY ;

Boucher, ES ;

Gandhi, PJ ;

Silva, MA .

AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY, 2004, 61 (16) :1676-1681

[6]

Collins R, 2002, LANCET, V360, P7, DOI 10.1016/S0140-6736(02)09327-3

[7]

In vivo anti-inflammatory effect of statins is mediated by nonsterol mevalonate products [J].

Diomede, L ;

Albani, D ;

Sottocorno, M ;

Donati, MB ;

Bianchi, M ;

Fruscella, P ;

Salmona, M .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2001, 21 (08) :1327-1332

[8]

Statin therapy prior to ICU admission: protection against infection or a severity marker? [J].

Fernandez, R ;

De Pedro, VJ ;

Artigas, A .

INTENSIVE CARE MEDICINE, 2006, 32 (01) :160-164

[9]

Simvastatin decreases nitric oxide overproduction and reverts the impaired vascular responsiveness induced by endotoxic shock in rats [J].

Giusti-Paiva, A ;

Martinez, MR ;

Felix, JVC ;

da Rocha, MJA ;

Carnio, EC ;

Elias, LLK ;

Antunes-Rodrigues, J .

SHOCK, 2004, 21 (03) :271-275

[10]

Simvastatin reduces NF-κB activity in peripheral mononuclear and in plaque cells of rabbit atheroma more markedly than lipid lowering diet [J].

Hernández-Presa, MA ;

Ortego, M ;

Tuñón, J ;

Martín-Ventura, JL ;

Mas, S ;

Blanco-Colio, LM ;

Aparicio, C ;

Ortega, L ;

Gómez-Gerique, J ;

Vivanco, F ;

Egido, J .

CARDIOVASCULAR RESEARCH, 2003, 57 (01) :168-177