Hydrophobically directed organic synthesis

被引：161

作者：

Lindström, UM ^{[1
]}

Andersson, F ^{[1
]}

机构：

[1] Lund Univ, Dept Organ Chem, S-22100 Lund, Sweden

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 04期

关键词：

hydrophobic effect; solvent effects; synthetic methods; water chemistry;

D O I：

10.1002/anie.200502882

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Going with the flow: Nature has perfected the use of hydrophobic interactions in biochemical processes. Some recent work on synthesis has shown that reactions in water may be predisposed to favor tran sition states that optimize hydrophobic interactions (see picture). Thus, it should in principle be possible to use hydrophobic interactions as a nonbonding element of control for synthetic reactions in water. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

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页码：548 / 551

页数：4

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