Vitamin D deficiency among the elderly: insights from Qatar

被引:12
作者
Alhamad, Hanadi Khamis [1 ]
Nadukkandiyil, Navas [1 ]
El-Menyar, Ayman [2 ,3 ,4 ]
Wahab, Luay Abdel [1 ]
Sankaranarayanan, Anoop [1 ]
Al Sulaiti, Essa Mubarak [1 ]
机构
[1] Hamad Med Corp, Al Rumailah Hosp, Doha, Qatar
[2] Weill Cornell Med Coll, Doha, Qatar
[3] Hamad Gen Hosp, Doha, Qatar
[4] Ahmed Maher Teaching Hosp, Cairo, Egypt
关键词
Elderly; Geriatrics; Qatar; Vitamin D deficiency; 25-HYDROXYVITAMIN D; METABOLIC SYNDROME; HYPERPARATHYROIDISM; ASSOCIATION; FRACTURES;
D O I
10.1185/03007995.2014.900003
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Objectives: Vitamin D (VitD) deficiency is associated with comorbidities in the elderly. The present study investigates the prevalence of VitD deficiency among the elderly in Qatar. Research design and methods: A retrospective study conducted between April 2010 and April 2012 that involved chart reviews. All elderly patients of age >= 65 years in geriatrics facilities including Rumailah hospital, skilled nursing facility and home healthcare services in Qatar were included in the study. Measurements: Patient characteristics and outcomes were analyzed and compared according to the severity of VitD deficiency. Correlation of VitD with comorbidities was analyzed. Mean follow-up period was 6 months. Results: A total of 889 patients were enrolled; the majority (66%) were females and the mean age was 75 +/- 8.7 years. Patient comorbidities included hypertension (76.5%), diabetes mellitus (63%), dyslipidemia, (47.5%), dementia (26%) coronary artery disease (24%) and cerebrovascular accident (24%). The mean baseline serum VitD level was 24.4 +/- 13.5 ng/ml; 72% of patients had VitD deficiency: mild (31%), moderate (30%) and severe (11%). Patients with severe VitD deficiency had significantly higher HbA(1c) levels compared with patients with optimal VitD (P=0.03). High density lipoprotein (HDL-C) levels were significantly lower in severe VitD deficiency patients compared with optimal VitD patients (P=0.04). There was a positive correlation between HDL-C and VitD level (r=0.17, P=0.001), whereas HbA(1c) levels showed negative correlation with VitD (r= -0.15, P=0.009). Conclusions: A high prevalence of VitD deficiency (72%) was observed among the elderly in Qatar. Lower VitD was associated with higher HbA(1c) and lower HDL-C levels. Further studies are warranted to evaluate whether VitD supplementation controls diabetes mellitus (DM) and low HDL-C levels among the elderly.
引用
收藏
页码:1189 / 1196
页数:8
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