Boron reagents in process chemistry: Excellent tools for selective reductions

被引：206

作者：

Burkhardt, Elizabeth R. ^{[1
]}

Matos, Karl ^{[1
]}

机构：

[1] BASF Corp, Evans City, PA 16033 USA

来源：

CHEMICAL REVIEWS | 2006年 / 106卷 / 07期

关键词：

D O I：

10.1021/cr0406918

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Borane and borohydride reagents are very important in the synthesis of critical drug intermediates. This review illustrates the use of these reagents with examples of hydroboration reactions and the application of the derived organoboron compounds in diverse reactions from alcohol synthesis to Suzuki-Miyaura coupling reactions. It also describes the use of organoboron reductants for the large-scale synthesis of alcohols, lactols, amines, and other classes of products.

引用

页码：2617 / 2650

页数：34

共 490 条

[1] Reductive amination of aldehydes and ketones with sodium triacetoxyborohydride. Studies on direct and indirect reductive amination procedures [J].

AbdelMagid, AF ;

Carson, KG ;

Harris, BD ;

Maryanoff, CA ;

Shah, RD .

JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (11) :3849-3862

[2] Reduction of amides by boranes [J].

Alcântara, AFD ;

dos Santos Barroso, H ;

Piló-Veloso, D .

QUIMICA NOVA, 2002, 25 (02) :300-311

[3]

Andersson P. G, 2001, WO Patent, Patent No. [WO0149649, 0149649]

[4]

ANGERBAUER R, 1993, Patent No. 177080

[5]

ANGERBAUER R, 1991, Patent No. 0325130

[6]

ANGERBAUER R, 1992, Patent No. 5169857

[7]

ANGERBAUER R, Patent No. 0491226

[8]

ANGERBAUER R, 1991, Patent No. 5006530

[9]

[Anonymous], [No title captured], Patent No. 9935146

[10]

ANTHONY NJ, 1999, Patent No. 5856326

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