Ketamine, Propofol, and Ketofol Use for Pediatric Sedation

被引:85
作者
Alletag, Michelle J. [1 ]
Auerbach, Marc A. [2 ]
Baum, Carl R. [2 ]
机构
[1] Univ Texas SW Med Ctr Dallas, Sect Pediat Emergency Med, Dallas, TX 75235 USA
[2] Yale Univ, Sch Med, New Haven, CT USA
关键词
ketofol; procedural sedation; ketamine; propofol; PROCEDURAL SEDATION; ADVERSE EVENTS; COMBINATION; ANESTHESIA; ANALGESIA; CHILDREN; EFFICACY; FENTANYL; TRIAL;
D O I
10.1097/PEC.0b013e318276fde2
中图分类号
R4 [临床医学];
学科分类号
100218 [急诊医学];
摘要
The use of a combination of ketamine and propofol (ketofol) for procedural sedation and analgesia in the emergency department setting shows promise as an agent that may minimize adverse effects of ketamine or propofol as single agents. This article provides a summary of current literature regarding ketofol. It also reviews the comparative pharmacokinetics, adverse effects, and dosing of ketamine, propofol, and ketofol as agents for procedural sedation and analgesia.
引用
收藏
页码:1391 / 1395
页数:5
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