Bronchiolitis obliterans organizing pneumonia (BOOP) after thoracic radiotherapy for breast carcinoma

被引:20
作者
Cornelissen, Robin [1 ,2 ]
Senan, Suresh [3 ]
Antonisse, Imogeen E. [4 ]
Liem, Hauw [5 ]
Tan, Youke K. Y. [1 ]
Rudolphus, Arjan [1 ]
Aerts, Joachim G. J. V. [1 ,2 ]
机构
[1] St Franciscus Gasthuis, Dept Pulm Dis, Rotterdam, Netherlands
[2] Erasmus MC, Dept Pulm Dis, Rotterdam, Netherlands
[3] Vrije Univ Amsterdam Med Ctr, Dept Radiat Oncol, Amsterdam, Netherlands
[4] Erasmus MC, Dept Radiat Oncol, Rotterdam, Netherlands
[5] Lievensberg Hosp, Dept Pulm Dis, Bergen Op Zoom, Netherlands
关键词
D O I
10.1186/1748-717X-2-2
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Common complications of thoracic radiotherapy include esophagitis and radiation pneumonitis. However, it is important to be aware of uncommon post-radiotherapy complications such as bronchiolitis obliterans organizing pneumonia (BOOP). We report on two patients with carcinoma of the breast who developed an interstitial lung disease consistent with BOOP. BOOP responds to treatment with corticosteroids and the prognosis is generally good despite of the need for long-term administration of corticosteroids as relapses can occur during tapering of steroids. This report provides guidelines for the evaluation and treatment of patients with pulmonary infiltrates after radiotherapy.
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页数:5
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