Cerebral activation during anal and rectal stimulation

被引:81
作者
Lotze, M [1 ]
Wietek, B
Birbaumer, N
Ehrhardt, J
Grodd, W
Enck, P
机构
[1] Univ Tubingen, Inst Med Psychol & Behav Neurobiol, D-72074 Tubingen, Germany
[2] Univ Tubingen, Dept Gen Surg, D-72074 Tubingen, Germany
[3] Univ Tubingen, Dept Neuroradiol, Sect Expt Magnet Resonance CNS, D-72074 Tubingen, Germany
[4] Univ Padua, Dept Gen Psychol, Padua, Italy
关键词
visceral; rectal; anal; somatosensory; fMRI;
D O I
10.1006/nimg.2001.0901
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
While the rectum is innervated by visceral afferents, the anal canal is innervated by the somatosensory pudendal nerve. The representation of these two central domains of intestinal sensations in the human brain is largely unknown. Nonpainful pneumatic stimulation of the anal canal and the distal rectum using event-related functional magnetic resonance imaging (fMRI) was performed in eight healthy subjects. Subjective scaling of sensations revealed no differences in unpleasantness and pain during both stimuli. Both types of stimuli revealed MM activation in secondary somatosensory, insula, cingular gyrus, left inferior parietal, and right orbitofrontal cortex. Anal stimulation resulted in additional activation of primary sensory and motor cortex, supplementary motor area, and left cerebellum. We concluded that viscerorectal and somatosensory anal stimulation predominantly differ in their primary sensory activation and additional activation in motor areas. This motor response following aversive somatosensory stimuli may be caused by a reflexive avoidance reaction which is not observed after the more diffuse experienced visceral stimulation. (C) 2001 Academic Press.
引用
收藏
页码:1027 / 1034
页数:8
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