Carbimazole embryopathy-bilateral choanal atresia and patent vitello-intestinal duct: A case report and review of literature

被引：11

作者：

Kannan, Lakshminarayanan ^{[1
]}

Mishra, Satish ^{[1
]}

Agarwal, Ramesh ^{[1
]}

Kartikeyan, Venkat ^{[2
]}

Gupta, Neerja ^{[1
]}

Kabra, Madhulika ^{[1
]}

机构：

[1] All India Inst Med Sci, Genet Subdiv, Dept Pediat, New Delhi 110029, India

[2] All India Inst Med Sci, Dept ENT, New Delhi 110029, India

来源：

BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY | 2008年 / 82卷 / 09期

关键词：

carbimazole; patent vitello-intestinal duct; choanal atresia; thyrotoxicosis; teratogenicity;

D O I：

10.1002/bdra.20483

中图分类号：

Q [生物科学];

学科分类号：

07 [理学]; 0710 [生物学]; 09 [农学];

摘要：

BACKGROUND: In utero exposure to carbimazole for maternal hyperthyroidism has been reported to cause choanal atresia. There are case reports of patent vitello-intestinal duct and Meckel's diverticulum in similar association. CASE: We report another such instance of an infant who was exposed to carbimazole in utero, presenting with bilateral choanal atresia and patent vitello-intestinal duct. CONCLUSIONS: As there seems to be no reports of a possible association between propylthiouracil and congenital malformations, it may be safer to use propylthiouracil instead of carbimazole.

引用

页码：649 / 651

页数：3

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