Medical management of radiation injuries: current approaches

被引：61

作者：

Berger, ME ^{[1
]}

Christensen, DM ^{[1
]}

Lowry, PC ^{[1
]}

Jones, OW ^{[1
]}

Wiley, AL ^{[1
]}

机构：

[1] REACTS, Oak Ridge, TN 37831 USA

来源：

OCCUPATIONAL MEDICINE-OXFORD | 2006年 / 56卷 / 03期

关键词：

combined injury; gastrointestinal syndrome; haematopoietic syndrome; internal contamination; local radiation injury; radiation injury; radiation medicine;

D O I：

10.1093/occmed/kql011

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The current approach to medical management of irradiated patients begins with early diagnosis of radiation injury. Medical assessment of radiation dose is based on event history, symptomatology and laboratory results, with emphasis on time to emesis and lymphocyte depletion kinetics. Dose assessment provides a basis for early use of haematopoietic growth factors that can shorten the period of neutropaenia for patients with acute radiation syndrome. Assessments of haematopoietic, gastrointestinal and cutaneous syndromes have improved in recent years, but treatment options remain limited. Selected examples of current developments are presented.

引用

页码：162 / 172

页数：11

共 67 条

[1]

*AFRRI, MED MAN RAD INJ CURR

[2]

Akashi M, 2002, MEDICAL BASIS FOR RADIATION-ACCIDENT PREPAREDNESS, P303

[3]

ANDREWS GA, 1980, MED BASIS RAD ACCIDE, P297

[4] SYMPTOMATOLOGY OF ACUTE RADIATION EFFECTS IN HUMANS AFTER EXPOSURE TO DOSES OF 0.5-30 GY [J].

ANNO, GH ;

BAUM, SJ ;

WITHERS, HR ;

YOUNG, RW .

HEALTH PHYSICS, 1989, 56 (06) :821-838

[5]

[Anonymous], 2001, MED MANAGEMENT RAD A

[6]

Barabanova AV, 2002, MEDICAL BASIS FOR RADIATION-ACCIDENT PREPAREDNESS, P217

[7] Chemotherapy- and radiotherapy-induced intestinal damage is regulated by intestinal trefoil factor [J].

Beck, PL ;

Wong, JF ;

Li, Y ;

Swaminathan, S ;

Xavier, RJ ;

Devaney, KL ;

Podolsky, DK .

GASTROENTEROLOGY, 2004, 126 (03) :796-808

[8]

Berger M, HOSP TRIAGE 1 24 HOU

[9] Colonic toxicity of administered drugs and chemicals [J].

Cappell, MS .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2004, 99 (06) :1175-1190

[10] Sucralfate in the prevention of radiation-induced oral mucositis [J].

Cengiz, M ;

Özyar, E ;

Öztürk, D ;

Akyol, F ;

Atahan, IL ;

Hayran, M .

JOURNAL OF CLINICAL GASTROENTEROLOGY, 1999, 28 (01) :40-43

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