The effect of n-3 fatty acids on low density lipoprotein subfractions

被引：31

作者：

Griffin, BA ^{[1
]}

机构：

[1] Univ Surrey, Ctr Nutr & Food Safety, Sch Biomed & Life Sci, Guildford GU2 7XH, Surrey, England

来源：

LIPIDS | 2001年 / 36卷

关键词：

D O I：

10.1007/s11745-001-0688-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A predominance of small, dense low density lipoprotein (LDL) represents a significant source of increased risk for the development of coronary heart disease in Westernized countries. Dietary long-chain n-3 polyunsaturated fatty acids exert a potent triglyceride-lowering effect that redistributes LDL subfractions toward larger and lighter particles. These dietary fatty acids thus have a key role to play in providing protection against this particularly atherogenic type of LDL.

引用

页码：S91 / S97

页数：7

共 41 条

[1] Influence of plasma lipid and LDL-subfraction profile on the interaction between low density lipoprotein with human arterial wall proteoglycans [J].

Anber, V ;

Griffin, BA ;

McConnell, M ;

Packard, CJ ;

Shepherd, J .

ATHEROSCLEROSIS, 1996, 124 (02) :261-271

[2]

AUSTIN MA, 1988, JAMA-J AM MED ASSOC, V260, P1917

[3] ATHEROGENIC LIPOPROTEIN PHENOTYPE - A PROPOSED GENETIC-MARKER FOR CORONARY HEART-DISEASE RISK [J].

AUSTIN, MA ;

KING, MC ;

VRANIZAN, KM ;

KRAUSS, RM .

CIRCULATION, 1990, 82 (02) :495-506

[4]

BANG HO, 1976, ACTA MED SCAND, V200, P69

[5]

BARBIRAK SP, 1992, ARTERIOSCLER THROMB, V12, P1176

[6] INFLUENCE OF N-3 FATTY-ACIDS FROM FISH OILS ON CONCENTRATION OF HIGH-DENSITY AND LOW-DENSITY-LIPOPROTEIN SUBFRACTIONS AND THEIR LIPID AND APOLIPOPROTEIN COMPOSITION [J].

BAUMSTARK, MW ;

FREY, I ;

BERG, A ;

KEUL, J .

CLINICAL BIOCHEMISTRY, 1992, 25 (05) :338-340

[7]

Bjorkegren J, 1996, J LIPID RES, V37, P76

[8] EVIDENCE FOR A COMMON, SATURABLE, TRIGLYCERIDE REMOVAL MECHANISM FOR CHYLOMICRONS AND VERY LOW-DENSITY LIPOPROTEINS IN MAN [J].

BRUNZELL, JD ;

HAZZARD, WR ;

PORTE, D ;

BIERMAN, EL .

JOURNAL OF CLINICAL INVESTIGATION, 1973, 52 (07) :1578-1585

[9] IMPAIRED CHYLOMICRON REMNANT CLEARANCE IN FAMILIAL COMBINED HYPERLIPIDEMIA [J].

CABEZAS, MC ;

DEBRUIN, TWA ;

JANSEN, H ;

KOCK, LAW ;

KORTLANDT, W ;

ERKELENS, DW .

ARTERIOSCLEROSIS AND THROMBOSIS, 1993, 13 (06) :804-814

[10] SUSCEPTIBILITY OF SMALL, DENSE, LOW-DENSITY LIPOPROTEINS TO OXIDATIVE MODIFICATION IN SUBJECTS WITH THE ATHEROGENIC LIPOPROTEIN PHENOTYPE, PATTERN-B [J].

CHAIT, A ;

BRAZG, RL ;

TRIBBLE, DL ;

KRAUSS, RM .

AMERICAN JOURNAL OF MEDICINE, 1993, 94 (04) :350-356

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