Geno3D:: automatic comparative molecular modelling of protein

被引：328

作者：

Combet, C ^{[1
]}

Jambon, M ^{[1
]}

Deléage, G ^{[1
]}

Geourjon, C ^{[1
]}

机构：

[1] Inst Biol & Chim Prot, CNRS, IBCP, UMR 5086,NMR, F-69367 Lyon 07, France

来源：

BIOINFORMATICS | 2002年 / 18卷 / 01期

关键词：

D O I：

10.1093/bioinformatics/18.1.213

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Geno3D (http://geno3d-pbil.ibcp.fr) is an automatic web server for protein molecular modelling. Starting with a query protein sequence, the server performs the homology modelling in six successive steps: (1) identify homologous proteins with known 3D structures by using PSI-BLAST; (5) provide the user all potential templates through a very convenient user interface for target selection; (iii) perform the alignment of both query and subject sequences; (iv) extract geometrical restraints (dihedral angles and distances) for corresponding atoms between the query and the template; (v) perform the 3D construction of the protein by using a distance geometry approach and (vi) finally send the results by e-mail to the user. Availability: Free to academic users http://geno3d-pbil. ibcp.fr Contact: c.geourjoni@ibcp.fr.

引用

页码：213 / 214

页数：2

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