An update on the use of helminths to treat Crohn's and other autoimmunune diseases

被引:36
作者
Reddy, Aditya [1 ]
Fried, Bernard [1 ]
机构
[1] Lafayette Coll, Dept Biol, Easton, PA 18042 USA
关键词
TRICHURIS-SUIS THERAPY; NECATOR-AMERICANUS; INFECTIONS; WORMS; SAFE;
D O I
10.1007/s00436-008-1297-5
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
This review updates our previous one (Reddy and Fried, Parasitol Research 100: 921-927, 2007) on Crohn's disease and helminths. The review considers the most recent literature on Trichuris suis therapy and Crohn's and the significant literature on the use of Necator americanus larvae to treat Crohn's and other autoimmune disorders. The pros and cons of helminth therapy as related to autoimmune disorders are discussed in the review. We also discuss the relationship of the bacterium Campylobacter jejuni and T. suis in Crohn's disease. The significant literature on helminths other than N. americanus and T. suis as related to autoimmune diseases is also reviewed.
引用
收藏
页码:217 / 221
页数:5
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