The activity of leukocyte NADPH oxidase:: Regulation by p47PHOX cysteine and serine residues

被引：31

作者：

Babior, BM ^{[1
]}

机构：

[1] Scripps Res Inst, La Jolla, CA 92037 USA

来源：

ANTIOXIDANTS & REDOX SIGNALING | 2002年 / 4卷 / 01期

关键词：

D O I：

10.1089/152308602753625834

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The leukocyte NADPH oxidase is regulated chiefly by phosphorylation of the serines of p47(PHOX). one of its cytosolic subunits. Its activity is also regulated, however, by the four cysteines of the same subunit, as indicated by the replacement of those cysteines by alanines.

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页码：35 / 38

页数：4

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