Plasma endothelin-1 and tumor necrosis factor-alpha concentrations in pregnant and cyclic rats after low-dose endotoxin infusion

被引：7

作者：

Faas, MM ^{[1
]}

Bakker, WW ^{[1
]}

Valkhof, N ^{[1
]}

Baller, JFW ^{[1
]}

Schuiling, GA ^{[1
]}

机构：

[1] UNIV GRONINGEN,DEPT PATHOL,NL-9700 RB GRONINGEN,NETHERLANDS

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1997年 / 177卷 / 02期

关键词：

endothelin-1; tumor necrosis factor-alpha; endotoxin; pregnancy; rat;

D O I：

10.1016/S0002-9378(97)70210-2

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Plasma endothelin-1 and tumor necrosis factor-alpha were determined in pregnant and cyclic rats after infusion of either endotoxin (1.0 mu g/kg of body weight) or saline solution. After endotoxin, but not after saline solution, administration there was a transient endothelin-1 response in pregnant rats but not cyclic rats. In both reproductive conditions there was an equally high transient tumor necrosis factor-alpha response after endotoxin.

引用

页码：429 / 430

页数：2

共 3 条

[1] A NEW ANIMAL-MODEL FOR HUMAN PREECLAMPSIA - ULTRA-LOW-DOSE ENDOTOXIN INFUSION IN PREGNANT RATS [J].

FAAS, MM ;

SCHUILING, GA ;

BALLER, JFW ;

VISSCHER, CA ;

BAKKER, WW .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1994, 171 (01) :158-164

[2] MODULATION OF CIRCULATING ENDOTHELIN LEVELS IN HYPERTENSION AND ENDOTOXEMIA IN RATS [J].

VEMULAPALLI, S ;

CHIU, PJS ;

RIVELLI, M ;

FOSTER, CJ ;

SYBERTZ, EJ .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1991, 18 (06) :895-903

[3] ENDOTHELIN EXCRETION IN HYPERTENSIVE PREGNANCY - RELATIONSHIP TO GLOMERULAR-FILTRATION RATE, BLOOD-PRESSURE, AND SODIUM-EXCRETION [J].

WANG, MX ;

BROWN, MA ;

BUDDLE, ML ;

CARLTON, MA ;

CARIO, GM ;

WHITWORTH, JA .

AMERICAN JOURNAL OF HYPERTENSION, 1994, 7 (04) :308-313

← 1 →