MHC class I genes of the tree shrew Tupaia belangeri

被引:14
作者
Flügge, P
Fuchs, E
Günther, E
Walter, L
机构
[1] Univ Gottingen, Immungenet Abt, D-37073 Gottingen, Germany
[2] Deutsch Primatenzentrum GmbH, Abt Neurobiol, D-37077 Gottingen, Germany
关键词
Tupaia; class I genes; evolution; major histocompatibility complex;
D O I
10.1007/s00251-001-0401-0
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Two MHC class I cDNA sequences from the tree shrew (Tupaia belangeri), Tube-W01 and Tube-W02, have been isolated which are probably derived from classical class I genes. Expression of the tupaia class I genes was investigated in several organs, in particular the brain, in which slightly different amounts of class I transcripts are detectable in different areas. Gene tree analysis performed with Tube-W01 and Tube-W02, and including class I sequences derived from other orders, indicated that the tupaia sequences cluster differently from Primates, Carnivora, Artiodactyla, Perissodactyla, and Rodentia, but might be related to Lagomorpha class I genes.
引用
收藏
页码:984 / 988
页数:5
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