Novel Paramyxovirus Associated with Severe Acute Febrile Disease, South Sudan and Uganda, 2012

被引：45

作者：

Albarino, Cesar G. ^{[1
]}

Foltzer, Michael ^{[2
]}

Towner, Jonathan S. ^{[1
]}

Rowe, Lory A. ^{[1
]}

Campbell, Shelley ^{[1
]}

Jaramillo, Carlos M. ^{[2
]}

Bird, Brian H. ^{[1
]}

Reeder, DeeAnn M. ^{[3
]}

Vodzak, Megan E. ^{[3
]}

Rota, Paul ^{[1
]}

Metcalfe, Maureen G. ^{[1
]}

Spiropoulou, Christina F. ^{[1
]}

Knust, Barbara ^{[1
]}

Vincent, Joel P. ^{[1
]}

Frace, Michael A. ^{[1
]}

Nichol, Stuart T. ^{[1
]}

Rollin, Pierre E. ^{[1
]}

Stroeher, Ute ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA

[2] Geisinger Med Ctr, Danville, PA 17822 USA

[3] Bucknell Univ, Lewisburg, PA 17837 USA

来源：

EMERGING INFECTIOUS DISEASES | 2014年 / 20卷 / 02期

关键词：

VIRUS; BATS;

D O I：

10.3201/eid2002.131620

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In 2012, a female wildlife biologist experienced fever, malaise, headache, generalized myalgia and arthralgia, neck stiffness, and a sore throat shortly after returning to the United States from a 6-week field expedition to South Sudan and Uganda. She was hospitalized, after which a maculopapular rash developed and became confluent. When the patient was discharged from the hospital on day 14, arthralgia and myalgia had improved, oropharynx ulcerations had healed, the rash had resolved without desquamation, and blood counts and hepatic enzyme levels were returning to reference levels. After several known suspect pathogens were ruled out as the cause of her illness, deep sequencing and metagenomics analysis revealed a novel paramyxovirus related to rubula-like viruses isolated from fruit bats.

引用

页码：211 / 216

页数：6

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