Characterization of endonuclease III (nth) and endonuclease VIII (nei) mutants of Escherichia coli K-12

被引：84

作者：

Saito, Y

Uraki, F

Nakajima, S

Asaeda, A

Ono, K

Kubo, K

Yamamoto, K

机构：

[1] TOHOKU UNIV,GRAD SCH SCI,INST BIOL,SENDAI,MIYAGI 98077,JAPAN

[2] UNIV OSAKA PREFECTURE,SCH VET MED,DEPT RADIOL,SAKAI,OSAKA 593,JAPAN

来源：

JOURNAL OF BACTERIOLOGY | 1997年 / 179卷 / 11期

关键词：

D O I：

10.1128/jb.179.11.3783-3785.1997

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The nth and nei genes of Escherichia coli affect the production of endonuclease III and endonuclease WI, respectively, glycosylases/apurinic lyases that attack DNA damaged by oxidizing agents. Here, we provide evidence that oxidative lethal lesions are repaired by both endonuclease In, and endonuclease VIII and that spontaneous mutagenic lesions are repaired mainly by endonuclease III.

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页码：3783 / 3785

页数：3

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