Syntheses of 5′-O-glycosylnucleosides

被引：36

作者：

Liu, ZJ ^{[1
]}

Zhou, M ^{[1
]}

Min, JM ^{[1
]}

Zhang, LH ^{[1
]}

机构：

[1] Beijing Med Univ, Sch Pharmaceut Sci, Beijing 100083, Peoples R China

来源：

TETRAHEDRON-ASYMMETRY | 1999年 / 10卷 / 11期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/S0957-4166(99)00214-1

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A general synthetic approach to 2,3-unsaturated glycosides connecting with nucleosides involving Ferrier rearrangements of glycals is discussed. The new compounds were identified by NMR and MS (HRFAB(+)). The hydroxylation of the resulting 2,3-unsaturated glycosides was completed using OsO4 to give 5'-O-glycosylnucleosides in good yield. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：2119 / 2127

页数：9

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