Forward frontal fields: phylogeny and fundamental function

被引:326
作者
Wise, Steven P. [1 ]
机构
[1] NIMH, Sect Neurophysiol, Lab Syst Neurosci, Bethesda, MD 20892 USA
关键词
D O I
10.1016/j.tins.2008.08.008
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The largest part of the primate prefrontal cortex has no homolog in other mammals. Accordingly, it probably confers some advantage that other mammals either lack or attain through the function of other structures. Yet, this advantage remains enigmatic. This is not so for other parts of the cortex. For example, certain visual areas encode, represent and store knowledge about objects. By analogy, perhaps the primate prefrontal cortex encodes, represents and stores knowledge about behaviors, including the consequences of doing (or not doing) something in complex and challenging situations. The long list of functions often attributed to the prefrontal cortex could contribute to knowing what to do and what will happen when rare risks arise or outstanding opportunities knock.
引用
收藏
页码:599 / 608
页数:10
相关论文
共 79 条
[1]  
ALHAI J, 2005, LOBOTOMIST MAVERICK
[2]  
[Anonymous], 1949, PHYSL NERVOUS SYSTEM
[3]   Parallel processing of serial movements in prefrontal cortex [J].
Averbeck, BB ;
Chafee, MV ;
Crowe, DA ;
Georgopoulos, AP .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (20) :13172-13177
[4]   Prefrontal cortex and decision making in a mixed-strategy game [J].
Barraclough, DJ ;
Conroy, ML ;
Lee, D .
NATURE NEUROSCIENCE, 2004, 7 (04) :404-410
[5]   COMPARISON OF THE EFFECTS OF FRONTAL AND CAUDATE LESIONS ON DELAYED RESPONSE AND ALTERNATION IN MONKEYS [J].
BATTIG, K ;
ROSVOLD, HE ;
MISHKIN, M .
JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY, 1960, 53 (04) :400-404
[6]   TOPOGRAPHICAL ORGANIZATION AND RELATIONSHIP WITH VENTRAL STRIATAL COMPARTMENTS OF PREFRONTAL CORTICOSTRIATAL PROJECTIONS IN THE RAT [J].
BERENDSE, HW ;
GALISDEGRAAF, Y ;
GROENEWEGEN, HJ .
JOURNAL OF COMPARATIVE NEUROLOGY, 1992, 316 (03) :314-347
[7]   THE PATTERNS OF AFFERENT INNERVATION OF THE CORE AND SHELL IN THE ACCUMBENS PART OF THE RAT VENTRAL STRIATUM - IMMUNOHISTOCHEMICAL DETECTION OF RETROGRADELY TRANSPORTED FLUOROGOLD [J].
BROG, JS ;
SALYAPONGSE, A ;
DEUTCH, AY ;
ZAHM, DS .
JOURNAL OF COMPARATIVE NEUROLOGY, 1993, 338 (02) :255-278
[8]   Rodent models of prefrontal cortical function [J].
Brown, VJ ;
Bowman, EM .
TRENDS IN NEUROSCIENCES, 2002, 25 (07) :340-343
[9]   Prefrontal cortex function in the representation of temporally complex events [J].
Browning, Philip G. F. ;
Gaffan, David .
JOURNAL OF NEUROSCIENCE, 2008, 28 (15) :3934-3940
[10]   Frontal-temporal disconnection abolishes object discrimination learning set in macaque monkeys [J].
Browning, Philip G. F. ;
Easton, Alexander ;
Gaffan, David .
CEREBRAL CORTEX, 2007, 17 (04) :859-864