Studies on pyrrolidinones:: Some attempts to improve the anticancer properties of methyl N-(3,4,4′,5-tetramethoxybenzhydryl)pyroglutamate (HEI 81)

被引：8

作者：

Bourry, A

Rigo, B

Sanz, G

Couturier, D

机构：

[1] Ecole Hautes Etud Ind, Grp Rech Inhibit Proliferat Cellulaire, F-59046 Lille, France

[2] Janssen Res Fdn, F-27106 Val De Reuil, France

[3] Univ Sci & Technol, Lab Ingn Mol, F-59655 Villeneuve Dascq, France

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2002年 / 39卷 / 01期

关键词：

D O I：

10.1002/jhet.5570390117

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of esters, amides, pyrrolidinone and succinimide analogs of a new inhibitor of tubulin polymerization, methyl N-(3,4,4',5-tetramethoxybenzhydryl)pyroglutamate (HEI 8 1) was studied.

引用

页码：119 / 124

页数：6

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