Preliminary evaluation of Kielmeyera coriacea leaves extract on the central nervous system

被引：18

作者：

Audi, EA ^{[1
]}

Otobone, F ^{[1
]}

Martins, JVC ^{[1
]}

Cortez, DAG ^{[1
]}

机构：

[1] Univ Estadual Maringa, Dept Pharm & Pharmacol, Maringa, Parana, Brazil

来源：

FITOTERAPIA | 2002年 / 73卷 / 06期

关键词：

Kielmeyera coriacea; anxiolytic activity; antidepressive activity;

D O I：

10.1016/S0367-326X(02)00183-1

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

The hydroalcoholic extract of Kielmeyera coriacea leaves was evaluated for effects on the central nervous system by means of behavioral models which included forced swimming, open-field and elevated plus-maze tests. According to the results, K. coriacea leaves extract is effective as anxiolytic but not as an antidepressant drug. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：517 / 519

页数：3

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