Systems biology:: Metabolic balance sheets

被引：12

作者：

Cornish-Bowden, A ^{[1
]}

Cárdenas, ML ^{[1
]}

机构：

[1] CNRS, Lab Bioenerget & Ingn Prot, F-13402 Marseille 20, France

来源：

NATURE | 2002年 / 420卷 / 6912期

关键词：

Genes; -; Microorganisms;

D O I：

10.1038/420129a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Application of book-keeping principles to metabolic networks provides a powerful technique for understanding the properties of microorganisms and predicting the results of genetic modification.

引用

页码：129 / 130

页数：2

共 4 条

[1] Reverse engineering of biological complexity [J].

Csete, ME ;

Doyle, JC .

SCIENCE, 2002, 295 (5560) :1664-1669

[2] Exploring the pathway structure of metabolism: decomposition into subnetworks and application to Mycoplasma pneumoniae [J].

Schuster, S ;

Pfeiffer, T ;

Moldenhauer, F ;

Koch, I ;

Dandekar, T .

BIOINFORMATICS, 2002, 18 (02) :351-361

[3] Metabolic network structure determines key aspects of functionality and regulation [J].

Stelling, J ;

Klamt, S ;

Bettenbrock, K ;

Schuster, S ;

Gilles, ED .

NATURE, 2002, 420 (6912) :190-193

[4] Stoichiometric model for evaluating the metabolic capabilities of the facultative methylotroph Methylobacterium extorquens AM1, with application to reconstruction of C3 and C4 metabolism [J].

Van Dien, SJ ;

Lidstrom, ME .

BIOTECHNOLOGY AND BIOENGINEERING, 2002, 78 (03) :296-312

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