Structure of benzyl T-antigen disaccharide bound to Amaranthus caudatus agglutinin

被引：70

作者：

Transue, TR

Smith, AK

Mo, HQ

Goldstein, IJ

Saper, MA

机构：

[1] UNIV MICHIGAN, DIV BIOPHYS RES, ANN ARBOR, MI 48109 USA

[2] UNIV MICHIGAN, DEPT BIOL CHEM, ANN ARBOR, MI 48109 USA

来源：

NATURE STRUCTURAL BIOLOGY | 1997年 / 4卷 / 10期

关键词：

D O I：

10.1038/nsb1097-779

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Amaranthus caudatus agglutinin contains a novel arrangement of four beta-trefoil domains. The sugar-binding site provides specificity for the carcinoma-associated T-antigen disaccharide even when 'masked' by other sugars.

引用

页码：779 / 783

页数：5

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