Bioactive polysaccharides from Costus spicatus

被引：18

作者：

da Silva, BP ^{[1
]}

Parente, JP ^{[1
]}

机构：

[1] Univ Fed Rio de Janeiro, Lab Quim Plantas Med Nucl Pesquisas Prod Nat, Ctr Ciencias Saude, BR-21944970 Rio De Janeiro, Brazil

来源：

CARBOHYDRATE POLYMERS | 2003年 / 51卷 / 03期

关键词：

Costus spicatus; Costaceae; polysaccharides; antiinflammatory activity; phagocytic activity;

D O I：

暂无

中图分类号：

O69 [应用化学];

学科分类号：

081704 [应用化学];

摘要：

Three polysaccharides, glucans with mean M-r's of 7.50 X 10(5), 4.25 X 10(5) and 2.15 X 10(5), were isolated from fresh stems of Costus spicatus by fractionation on Sephacryl S-300 HR and Sephadex G-25. Chemical and spectroscopic studies indicated that they have a highly branched glucan type structure composed of alpha-(1 --> 4) linked D-glucopyranose residues with (1 --> 3), (1 --> 6) branching points, and a small amount of (1 --> 6) branching to alpha-(1 --> 3) linked D-glucopyranose residues. The polysaccharides inhibit capillary permeability and demonstrate phagocytosis stimulating properties. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：239 / 242

页数：4

共 18 条

[1]

BIOZZI G, 1953, BRIT J EXP PATHOL, V34, P441

[2]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[3]

ANTIINFLAMMATORY AND VASOPROTECTIVE ACTIVITIES OF POLYSACCHARIDES ISOLATED FROM FRUIT BODIES OF HIGHER FUNGI .1. POLYSACCHARIDES FROM TRAMETES GIBBOSA (PERS, FR)FR (POLYPORACEAE) [J].

CZARNECKI, R ;

GRZYBEK, J .

PHYTOTHERAPY RESEARCH, 1995, 9 (02) :123-127

[4]

da Silva BP, 1999, PLANTA MED, V65, P285

[5]

Da Silva BP, 1999, PHYTOCHEMISTRY, V51, P931

[6]

Flavonol glycosides from Costus spicatus [J].

da Silva, BP ;

Bernardo, RR ;

Parente, JP .

PHYTOCHEMISTRY, 2000, 53 (01) :87-92

[7]

DUBOIS M, 1956, ANAL CHEM, V28, P3

[8]

DETERMINATION OF D AND L CONFIGURATION OF NEUTRAL MONOSACCHARIDES BY HIGH-RESOLUTION CAPILLARY GLC [J].

GERWIG, GJ ;

KAMERLING, JP ;

VLIEGENTHART, JFG .

CARBOHYDRATE RESEARCH, 1978, 62 (02) :349-357

[9]

GONDA R, 1992, CHEM PHARM BULL, V40, P185, DOI 10.1248/cpb.40.185

[10]

CHARACTERIZATION BY GAS-LIQUID CHROMATOGRAPHY MASS SPECTROMETRY AND PROTON-MAGNETIC-RESONANCE SPECTROSCOPY OF PERTRIMETHYLSILYL METHYL GLYCOSIDES OBTAINED IN METHANOLYSIS OF GLYCOPROTEINS AND GLYCOPEPTIDES [J].

KAMERLING, JP ;

GERWIG, GJ ;

VLIEGENTHART, JFG ;

CLAMP, JR .

BIOCHEMICAL JOURNAL, 1975, 151 (03) :491-495

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