Virus evolution - The importance of being erroneous

被引：33

作者：

Bonhoeffer, S ^{[1
]}

Sniegowski, P

机构：

[1] Swiss Fed Inst Technol, Dept Environm Sci, CH-8092 Zurich, Switzerland

[2] Univ Penn, Dept Biol, Philadelphia, PA 19104 USA

来源：

NATURE | 2002年 / 420卷 / 6914期

关键词：

D O I：

10.1038/420367a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Viruses must mutate to survive in the face of attack by their host's immune system. A new model suggests that the viral mutation rate is optimized in an evolutionary trade-off between adaptability and genomic integrity.

引用

页码：367 / +

页数：2

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