Molecular design of aquaporin-1 water channel as revealed by electron crystallography

被引：104

作者：

Li, HL ^{[1
]}

Lee, S ^{[1
]}

Jap, BK ^{[1
]}

机构：

[1] UNIV CALIF BERKELEY,LAWRENCE BERKELEY LAB,DIV LIFE SCI,BERKELEY,CA 94720

来源：

NATURE STRUCTURAL BIOLOGY | 1997年 / 4卷 / 04期

关键词：

D O I：

10.1038/nsb0497-263

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The electron crystallographic structure of the aquaporin-1 water channel, determined at similar to 6 Angstrom, reveals that the protein has six transmembrane alpha-helices forming a trapezoid-like cylinder. There is a branched rod-like structure within the cylinder that traverses the membrane and likely contains at least one alpha-helix.

引用

页码：263 / 265

页数：3

共 23 条

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