Did Quadruplex DNA Play a Role in the Evolution of the Eukaryotic Linear Chromosome?

被引：5

作者：

Arthanari, Haribabu ^{[1
]}

Bolton, Philip H. ^{[1
]}

机构：

[1] Wesleyan Univ, Dept Chem, Middletown, CT 06459 USA

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2003年 / 3卷 / 01期

基金：

美国国家卫生研究院;

关键词：

DNA; telomere; quadruplex; tetraplex; evolution; linear chromosome;

D O I：

10.2174/1389557033405520

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The current evidence on prokaryotic linear chromosomes, the eukaryotes that do not use telomerase and quadruplex DNA has been considered. This has lead to the suggestion that quadruplex DNA may have played a role in the evolution of the protection linear chromosomes rather than in overcoming the end replication problem.

引用

页码：1 / 9

页数：9

共 64 条

[1] The 3′ non-coding region of the Drosophila melanogaster HeT-A telomeric retrotransposon contains sequences with propensity to form G-quadruplex DNA [J].

Abad, JP ;

Villasante, A .

FEBS LETTERS, 1999, 453 (1-2) :59-62

[2]

Arthanari H, 1999, ANTI-CANCER DRUG DES, V14, P317

[3] Functional and dysfunctional roles of quadruplex DNA in cells [J].

Arthanari, H ;

Bolton, PH .

CHEMISTRY & BIOLOGY, 2001, 8 (03) :221-230

[4] Telomerase as a possible target for anticancer therapy [J].

Autexier, C .

CHEMISTRY & BIOLOGY, 1999, 6 (11) :R299-R303

[5] DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes [J].

Bailey, SM ;

Meyne, J ;

Chen, DJ ;

Kurimasa, A ;

Li, GC ;

Lehnert, BE ;

Goodwin, EH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (26) :14899-14904

[6] Strand-specific postreplicative processing of mammalian telomeres [J].

Bailey, SM ;

Cornforth, MN ;

Kurimasa, A ;

Chen, DJ ;

Goodwin, EH .

SCIENCE, 2001, 293 (5539) :2462-2465

[7] HAIRPIN AND PARALLEL QUARTET STRUCTURES FOR TELOMERIC SEQUENCES [J].

BALAGURUMOORTHY, P ;

BRAHMACHARI, SK ;

MOHANTY, D ;

BANSAL, M ;

SASISEKHARAN, V .

NUCLEIC ACIDS RESEARCH, 1992, 20 (15) :4061-4067

[8] Terminal proteins essential for the replication of linear plasmids and chromosomes in Streptomyces [J].

Bao, K ;

Cohen, SN .

GENES & DEVELOPMENT, 2001, 15 (12) :1518-1527

[9]

Biessmann H, 1997, Ciba Found Symp, V211, P53

[10]

Biessmann H., 1997, CIBA F SYMP, V211, P67

← 1 2 3 4 5 6 7 →