Allele-specific gene expression uncovered

被引：172

作者：

Knight, JC ^{[1
]}

机构：

[1] Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England

来源：

TRENDS IN GENETICS | 2004年 / 20卷 / 03期

关键词：

D O I：

10.1016/j.tig.2004.01.001

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Genetic variation in populations can result in variation in levels of gene expression but the extent to which this occurs has been unclear. In this article, recent studies of allele-specific expression among autosomal non-imprinted genes are reviewed. These new data provide evidence that differential expression is relatively common and that allelic differences are heritable and can be highly context specific.

引用

页码：113 / 116

页数：4

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