A Review on Anti-Inflammatory Activity of Monoterpenes

被引:401
作者
da Silveira e Sa, Rita de Cassia [1 ]
Andrade, Luciana Nalone [2 ]
de Sousa, Damiao Pergentino [2 ]
机构
[1] Univ Fed Paraiba, Dept Physiol & Pathol, BR-58051970 Joao Pessoa, Paraiba, Brazil
[2] Univ Fed Sergipe, Dept Pharm, BR-49100000 Sao Cristovao, Sergipe, Brazil
关键词
monoterpenes; essential oils; natural products; medicinal plants; anti-inflammatory activity; inflammation; cytokines; immunomodulatory activity; asthma; allergy; NF-KAPPA-B; MEVALONATE KINASE-DEFICIENCY; ESSENTIAL OIL; IN-VITRO; NIGELLA-SATIVA; PROSTAGLANDIN E-2; PERILLYL ALCOHOL; INFLAMMATORY RESPONSE; RHEUMATOID-ARTHRITIS; EXPERIMENTAL COLITIS;
D O I
10.3390/molecules18011227
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
070307 [化学生物学]; 071010 [生物化学与分子生物学];
摘要
Faced with the need to find new anti-inflammatory agents, great effort has been expended on the development of drugs for the treatment of inflammation. This disorder reduces the quality of life and overall average productivity, causing huge financial losses. In this review the anti-inflammatory activity of 32 bioactive monoterpenes found in essential oils is discussed. The data demonstrate the pharmacological potential of this group of natural chemicals to act as anti-inflammatory drugs.
引用
收藏
页码:1227 / 1254
页数:28
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