Risk factors and effectiveness of preventive measures against influenza in the community

被引：24

作者：

Castilla, Jesus ^{[1
]}

Godoy, Pere ^{[2
]}

Dominguez, Angela ^{[3
]}

Martin, Vicente ^{[4
]}

Delgado-Rodriguez, Miguel ^{[5
]}

Martinez-Baz, Ivan ^{[1
]}

Baricot, Maretva

Soldevila, Nuria

Mayoral, Jose M. ^{[6
]}

Astray, Jenaro ^{[7
]}

Quintana, Jose M. ^{[8
]}

Canton, Rafael ^{[9
]}

Castro, Ady

Gonzalez-Candelas, Fernando ^{[10
]}

Alonso, Jordi ^{[11
]}

Saez, Marc ^{[12
]}

Tamames, Sonia ^{[13
]}

Pumarola, Tomas

机构：

[1] Inst Salud Publ Navarra, Pamplona 31003, Spain

[2] Generalitat Catalonia, Dept Salut, Barcelona, Spain

[3] Univ Barcelona, E-08007 Barcelona, Spain

[4] Univ Leon, Inst Biomed IBIOMED, E-24071 Leon, Spain

[5] Univ Jaen, Jaen, Spain

[6] Serv Vigilancia Andalucia, Seville, Spain

[7] Comunidad Madrid, Area Epidemiol, Madrid, Spain

[8] Hosp Galdakao Usansolo, Unidad Invest, Guipuzcoa, Spain

[9] Hosp Univ Ramon & Cajal, Madrid, Spain

[10] Univ Valencia, Ctr Super Invest Salud Publ, E-46003 Valencia, Spain

[11] IMIM Hosp Mar Res Inst, Barcelona, Spain

[12] Univ Girona, Res Grp Stat Appl Econ & Hlth GRECS, Girona, Spain

[13] Junta Castilla & Leon, Direcc Gen Salud Publ & Invest, Valladolid, Spain

来源：

INFLUENZA AND OTHER RESPIRATORY VIRUSES | 2013年 / 7卷 / 02期

关键词：

Epidemiology; infection control; influenza; public health; transmission; vaccine; HEALTH-CARE WORKERS; PANDEMIC H1N1 2009; NONPHARMACEUTICAL INTERVENTIONS; A H1N1; VACCINE EFFECTIVENESS; RESPIRATORY ILLNESS; ANTIGENIC MATCH; HAND HYGIENE; YOUNG-ADULTS; INFECTION;

D O I：

10.1111/j.1750-2659.2012.00361.x

中图分类号：

R51 [传染病];

学科分类号：

100201 [内科学];

摘要：

Please cite this paper as: Castilla etal. (2013) Risk factors and effectiveness of preventive measures against influenza in the community. Influenza and Other Respiratory Viruses 7(2) 177183. Background The role of different risk exposures and preventive measures against influenza has not been well established. Objective The aim of this study was to evaluate risk factors and measures to prevent influenza infection in the community. Methods We conducted a multicenter casecontrol study. Cases were 481 outpatients aged 18years or older with laboratory-confirmed influenza A(H1N1)09 in the 20092010 season in Spain. A control was selected for each case from outpatients from the same area matched by age and date of consultation. Information on risk situations, preventive measures and other variables was obtained by interview and review of the medical record. Results In the multivariate conditional logistic regression analysis, the risk of a diagnosis of influenza increased with the number of cohabitants (compared with <3 cohabitants, three cohabitants had an OR=1 center dot 80, 95% CI 1 center dot 122 center dot 89, and 5 cohabitants had an OR=2 center dot 66, 95% CI 1 center dot 315 center dot 41) and for health care workers (OR=2 center dot 94, 95% CI 1 center dot 535 center dot 66). The use of metropolitan public transport was associated with a lower frequency of a diagnosis of influenza (OR=0 center dot 45, 95% CI 0 center dot 300 center dot 68) but not the use of taxis or long-distance transport. The influenza A(H1N1)09 vaccine had a protective effect (OR=0 center dot 13, 95% CI 0 center dot 040 center dot 48), unlike hand washing after touching contaminated surfaces or the use of alcohol-based hand sanitizers. Conclusion The home environment appears to play an important role in the spread of influenza in adults, but not the use of public transport. Health care workers have a higher risk of contracting influenza. Vaccination was the most effective preventive measure.

引用

页码：177 / 183

页数：7

共 35 条

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Effect of hand hygiene on infectious disease risk in the community setting: A meta-analysis [J].