Definition, course, and outcome of mild cognitive impairment

被引：159

作者：

Smith, GE

Petersen, RC

Parisi, JE

Ivnik, RJ

Kokmen, E

Tangalos, EG

Waring, S

机构：

[1] Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN

[2] Department of Neurology, Mayo Clinic, Rochester, MN

[3] Department of Pathology, Mayo Clinic, Rochester, MN

[4] Division of Community Internal Medicine, Mayo Clinic, Rochester, MN

[5] Department of Health Sciences Research, Mayo Clinic, Rochester, MN

[6] Department of Psychiatry and Psychology, Mayo Clinic, Rochester

来源：

AGING NEUROPSYCHOLOGY AND COGNITION | 1996年 / 3卷 / 02期

关键词：

D O I：

10.1080/13825589608256619

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

Mild Cognitive Impairment (MCI) is a term which can be applied to a boundary area between dementia and normal aging. Criteria which reliably describe persons falling in this range of the cognitive continuum can be defined. These persons are at very high risk for developing dementia. Biologic and cognitive parameters including Apolipoprotein E genotype help to differentiate MCI persons who will progress to dementia in 2-4 years from those who will remain free from dementia over this interval.

引用

页码：141 / 147

页数：7

共 31 条

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