Fabricating optical fiber imaging sensors using inkjet printing technology: A pH sensor proof-of-concept

被引:41
作者
Carter, JC
Alvis, RM
Brown, SB
Langry, KC
Wilson, TS
McBride, MT
Myrick, ML
Cox, WR
Grove, ME
Colston, BW
机构
[1] Lawrence Livermore Natl Lab, Livermore, CA 94550 USA
[2] Univ S Carolina, Dept Chem & Biochem, Columbia, SC 29208 USA
[3] Microfab Technol Inc, Plano, TX 75074 USA
关键词
optical fiber; image guide; pH sensor; imaging; biosensor; microjet; inkjet; microdot;
D O I
10.1016/j.bios.2005.06.006
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
We demonstrate the feasibility of using Drop-on-Demand microjet printing technology for fabricating imaging sensors by reproducibly printing an array of photopolymerizable sensing elements, containing a pH sensitive indicator, on the surface of an optical fiber image guide. The reproducibility of the microjet printing process is excellent for microdot (i.e. micrometer-sized polymer) sensor diameter (92.2 +/- 2.2 mu m), height (35.0 +/- 1.0 mu m), and roundness (0.00072 +/- 0.00023). pH sensors were evaluated in terms of pH sensing ability (<= 2% sensor variation), response time, and hysteresis using a custom fluorescence imaging system. In addition, the microjet technique has distinct advantages over other fabrication methods, which are discussed in detail. (c) 2005 Published by Elsevier B.V.
引用
收藏
页码:1359 / 1364
页数:6
相关论文
共 20 条
  • [1] A FIBEROPTIC CHEMICAL SENSOR WITH DISCRETE SENSING SITES
    BARNARD, SM
    WALT, DR
    [J]. NATURE, 1991, 353 (6342) : 338 - 340
  • [2] Fiber-optic imaging for in-situ chemical measurements
    Carter, JC
    Egan, WJ
    Nair, RB
    Murphy, CJ
    Morgan, SL
    Angel, SM
    [J]. CHEMICAL, BIOCHEMICAL, AND ENVIRONMENTAL FIBER SENSORS X, 1999, 3540 : 210 - 221
  • [3] Microjet printing of high precision microlens array for packaging of fiber-optic components
    Chen, T
    Cox, WR
    Lenhard, D
    Hayes, DJ
    [J]. OPTOELECTRONIC INTERCONNECTS, INTEGRATED CIRCUITS, AND PACKAGING, 2002, 4652 : 136 - 141
  • [4] COX WR, 1995, P SOC PHOTO-OPT INS, V2383, P110, DOI 10.1117/12.209012
  • [5] Microjetted lenslet triplet fibers
    Cox, WR
    Chen, T
    Ussery, D
    Hayes, DJ
    Tatum, JA
    MacFarlane, DL
    [J]. OPTICS COMMUNICATIONS, 1996, 123 (4-6) : 492 - 496
  • [6] Simultaneous monitoring of pH, CO2 and O-2 using an optical imaging fiber
    Ferguson, JA
    Healey, BG
    Bronk, KS
    Barnard, SM
    Walt, DR
    [J]. ANALYTICA CHIMICA ACTA, 1997, 340 (1-3) : 123 - 131
  • [7] SINGLE FIBER OPTIC FLUORESCENCE PH PROBE
    FUH, MRS
    BURGESS, LW
    HIRSCHFELD, T
    CHRISTIAN, GD
    WANG, F
    [J]. ANALYST, 1987, 112 (08) : 1159 - 1163
  • [8] OPTICAL FLUORESCENCE AND ITS APPLICATION TO AN INTRAVASCULAR BLOOD-GAS MONITORING-SYSTEM
    GEHRICH, JL
    LUBBERS, DW
    OPITZ, N
    HANSMANN, DR
    MILLER, WW
    TUSA, JK
    YAFUSO, M
    [J]. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1986, 33 (02) : 117 - 132
  • [9] Fast temporal response fiber optic chemical sensors based on the photodeposition of micrometer-scale polymer arrays
    Healey, BG
    Walt, DR
    [J]. ANALYTICAL CHEMISTRY, 1997, 69 (11) : 2213 - 2216
  • [10] PHOTODEPOSITION OF MICROMETER-SCALE POLYMER PATTERNS ON OPTICAL IMAGING FIBERS
    HEALEY, BG
    FORAN, SE
    WALT, DR
    [J]. SCIENCE, 1995, 269 (5227) : 1078 - 1080