Targeting TNF-α receptors for neurotherapeutics

[1] Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (02) : 709 - 714

[2] Inflammation in central nervous system injury [J]. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2003, 358 (1438) : 1669 - 1677

[3] TNF neutralization in MS - Results of a randomized, placebo-controlled multicenter study [J]. NEUROLOGY, 1999, 53 (03) : 457 - 465

[4] TNFα promotes proliferation of oligodendrocyte progenitors and remyelination [J]. NATURE NEUROSCIENCE, 2001, 4 (11) : 1116 - 1122

[5] CONTROL OF ESTABLISHED EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS BY INHIBITION OF TUMOR-NECROSIS-FACTOR (TNF) ACTIVITY WITHIN THE CENTRAL-NERVOUS-SYSTEM USING MONOCLONAL-ANTIBODIES AND TNF RECEPTOR IMMUNOGLOBULIN FUSION PROTEINS [J]. EUROPEAN JOURNAL OF IMMUNOLOGY, 1994, 24 (09) : 2040 - 2048

[6] TUMOR-NECROSIS-FACTOR-ALPHA AND TUMOR-NECROSIS-FACTOR-BETA PROTECT NEURONS AGAINST AMYLOID BETA-PEPTIDE TOXICITY - EVIDENCE FOR INVOLVEMENT OF A KAPPA-B-BINDING FACTOR AND ATTENUATION OF PEROXIDE AND CA2+ ACCUMULATION [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (20) : 9328 - 9332

[7] Bizette C, 1996, Chirurgie, V121, P474

[8] Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism [J]. PROGRESS IN NEUROBIOLOGY, 2005, 76 (02) : 77 - 98

[9] Loss of NF-κB activity during cerebral ischemia and TNF cytotoxicity [J]. MOLECULAR MEDICINE, 1999, 5 (06) : 372 - 381

[10] Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors [J]. NATURE MEDICINE, 1996, 2 (07) : 788 - 794

[1] Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (02) : 709 - 714

[2] Inflammation in central nervous system injury [J]. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2003, 358 (1438) : 1669 - 1677

[3] TNF neutralization in MS - Results of a randomized, placebo-controlled multicenter study [J]. NEUROLOGY, 1999, 53 (03) : 457 - 465

[4] TNFα promotes proliferation of oligodendrocyte progenitors and remyelination [J]. NATURE NEUROSCIENCE, 2001, 4 (11) : 1116 - 1122

[5] CONTROL OF ESTABLISHED EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS BY INHIBITION OF TUMOR-NECROSIS-FACTOR (TNF) ACTIVITY WITHIN THE CENTRAL-NERVOUS-SYSTEM USING MONOCLONAL-ANTIBODIES AND TNF RECEPTOR IMMUNOGLOBULIN FUSION PROTEINS [J]. EUROPEAN JOURNAL OF IMMUNOLOGY, 1994, 24 (09) : 2040 - 2048

[6] TUMOR-NECROSIS-FACTOR-ALPHA AND TUMOR-NECROSIS-FACTOR-BETA PROTECT NEURONS AGAINST AMYLOID BETA-PEPTIDE TOXICITY - EVIDENCE FOR INVOLVEMENT OF A KAPPA-B-BINDING FACTOR AND ATTENUATION OF PEROXIDE AND CA2+ ACCUMULATION [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (20) : 9328 - 9332

[7] Bizette C, 1996, Chirurgie, V121, P474

[8] Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism [J]. PROGRESS IN NEUROBIOLOGY, 2005, 76 (02) : 77 - 98

[9] Loss of NF-κB activity during cerebral ischemia and TNF cytotoxicity [J]. MOLECULAR MEDICINE, 1999, 5 (06) : 372 - 381

[10] Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors [J]. NATURE MEDICINE, 1996, 2 (07) : 788 - 794