Quantitative phase contrast optimised cancerous cell differentiation via ptychography

被引：31

作者：

Claus, Daniel ^{[1
]}

Maiden, Andrew M. ^{[1
]}

Zhang, Fucai ^{[1
]}

Sweeney, Francis G. R. ^{[1
]}

Humphry, Martin J. ^{[2
]}

Schluesener, Hermann ^{[3
]}

Rodenburg, John M. ^{[1
]}

机构：

[1] Univ Sheffield, Kroto Res Inst, Sheffield S3 7HQ, S Yorkshire, England

[2] Phase Focus Ltd, Sheffield S3 7HQ, S Yorkshire, England

[3] Univ Tubingen, Div Immunopathol Nervous Syst, D-72076 Tubingen, Germany

来源：

OPTICS EXPRESS | 2012年 / 20卷 / 09期

基金：

英国工程与自然科学研究理事会;

关键词：

DIFFRACTION;

D O I：

10.1364/OE.20.009911

中图分类号：

O43 [光学];

学科分类号：

070207 [光学];

摘要：

This paper shows that visible-light ptychography can be used to distinguish quantitatively between healthy and tumorous unstained cells. Advantages of ptychography in comparison to conventional phase-sensitive imaging techniques are highlighted. A novel procedure to automatically refocus ptychographic reconstructions is also presented, which improves quantitative analysis. (C) 2012 Optical Society of America

引用

页码：9911 / 9918

页数：8

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Real-time self-induced nonlinear optical Zernike-type filter in a bacteriorhodopsin film [J].