Physiological plasma Gas6 levels do not influence platelet aggregation

被引:18
作者
Clauser, S [1 ]
Bachelot-Iozat, C
Fontana, P
Gaussem, P
Remones, V
Aiach, M
Borgel, D
机构
[1] Univ Paris 05, Fac Sci Pharmaceut & Biol, INSERM, Paris, France
[2] Fac Med, Dept Internal Med, Div Angiol & Haemostasis, Geneva, Switzerland
[3] Univ Hosp Geneva, Geneva, Switzerland
关键词
D O I
10.1161/01.ATV.0000201968.72967.f9
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:E22 / E22
页数:1
相关论文
共 8 条
[1]   Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy [J].
Angelillo-Scherrer, A ;
Burnier, L ;
Flores, N ;
Savi, P ;
DeMol, M ;
Schaeffer, P ;
Herbert, JM ;
Lemke, G ;
Goff, SP ;
Matsushima, GK ;
Earp, HS ;
Vesin, C ;
Hoylaerts, MF ;
Plaisance, S ;
Collen, D ;
Conway, EM ;
Wehrle-Haller, B ;
Carmeliet, P .
JOURNAL OF CLINICAL INVESTIGATION, 2005, 115 (02) :237-246
[2]   Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis [J].
Angelillo-Scherrer, A ;
de Frutos, PG ;
Aparicio, C ;
Melis, E ;
Savi, P ;
Lupu, F ;
Arnout, J ;
Dewerchin, M ;
Hoylaerts, MF ;
Herbert, M ;
Collen, D ;
Dahlbäck, B ;
Carmeliet, P .
NATURE MEDICINE, 2001, 7 (02) :215-221
[3]   Analysis of Gas6 in human platelets and plasma [J].
Balogh, I ;
Hafizi, S ;
Stenhoff, J ;
Hansson, K ;
Dahlbäck, B .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2005, 25 (06) :1280-1286
[4]   Elevated growth-arrest-specific protein 6 plasma levels in patients with severe sepsis [J].
Borgel, D ;
Clauser, S ;
Bornstain, C ;
Bièche, I ;
Bissery, A ;
Remones, V ;
Fagon, JY ;
Aiach, M ;
Diehl, JL .
CRITICAL CARE MEDICINE, 2006, 34 (01) :219-222
[5]   An intronic polyrnorphism in the PAR-1 gene is associated with platelet receptor density and the response to SFLLRN [J].
Dupont, A ;
Fontana, P ;
Bachelot-Loza, C ;
Reny, JL ;
Bièche, I ;
Desvard, F ;
Aiach, M ;
Gaussem, P .
BLOOD, 2003, 101 (05) :1833-1840
[6]   Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses [J].
Gould, WR ;
Baxi, SM ;
Schroeder, R ;
Peng, YW ;
Leadley, RJ ;
Peterson, JT ;
Perrin, LA .
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2005, 3 (04) :733-741
[7]   Release of a product of growth arrest-specific gene 6 from rat platelets [J].
Ishimoto, Y ;
Nakano, T .
FEBS LETTERS, 2000, 466 (01) :197-199
[8]   THE PROTEIN ENCODED BY A GROWTH ARREST-SPECIFIC GENE (GAS6) IS A NEW MEMBER OF THE VITAMIN-K-DEPENDENT PROTEINS RELATED TO PROTEIN-S, A NEGATIVE COREGULATOR IN THE BLOOD-COAGULATION CASCADE [J].
MANFIOLETTI, G ;
BRANCOLINI, C ;
AVANZI, G ;
SCHNEIDER, C .
MOLECULAR AND CELLULAR BIOLOGY, 1993, 13 (08) :4976-4985