Titanocene(III) Chloride-Mediated Reductions of Oxazines, Hydroxamic Acids, and N-Hydroxy Carbamates

被引：54

作者：

Cesario, Cara ^{[1
]}

Tardibono, Lawrence P., Jr. ^{[1
]}

Miller, Marvin J. ^{[1
]}

机构：

[1] Univ Notre Dame, Dept Chem & Biochem, Notre Dame, IN 46545 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2009年 / 74卷 / 01期

关键词：

BETA-LACTAM ANTIBIOTICS; LOW-VALENT TITANIUM; DIELS-ALDER CYCLOADDUCTS; ORGANIC-SYNTHESIS; <<3(S)-(ACYLAMINO)-2-OXO-1-AZETIDINYL>OXY>ACETIC ACIDS; BIOLOGICAL-ACTIVITY; RING OPENINGS; CYCLIZATION; GENERATION; CHEMISTRY;

D O I：

10.1021/jo802184y

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Titanocene(III) chloride (Cp2TiCl), generated in situ, reduces N-O bonds of various substrates in good to excellent yields (72-95%). Reactions may be performed with stoichiometric Cp2TiCl or with catalytic Cp2TiCl.

引用

页码：448 / 451

页数：4

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