Primary immunodefciency diseases: an update on the classification from the International Union of Immunological Societies Expert Committee for Priary Immunodeficiency

被引：283

作者：

Al-Herz, Waleed ^{[1
,2
]}

Bousfiha, Aziz ^{[3
]}

Casanova, Jean-Laurent ^{[4
,5
,6
]}

Chapel, Helen ^{[7
]}

Conley, Mary Ellen ^{[8
,9
]}

Cunningham-Rundles, Charlotte ^{[10
]}

Etzioni, Amos ^{[11
]}

Fischer, Alain ^{[12
]}

Luis Franco, Jose ^{[13
]}

Geha, Raif S. ^{[14
]}

Hammarstrom, Lennart ^{[15
]}

Nonoyama, Shigeaki ^{[16
]}

Notarangelo, Luigi Daniele ^{[14
,17
]}

Ochs, Hans Dieter ^{[18
,19
]}

Puck, Jennifer M. ^{[20
,21
]}

Roifman, Chaim M. ^{[22
,23
]}

Seger, Reinhard ^{[24
]}

Tang, Mimi L. K. ^{[25
,26
,27
]}

机构：

[1] Kuwait Univ, Dept Pediat, Kuwait, Kuwait

[2] Al Sabah Hosp, Dept Pediat, Allergy & Clin Immunol Unit, Kuwait, Kuwait

[3] King Hassan II Univ, Casablanca Children Hosp, Ibn Rochd Med Sch, Clin Immunol Unit, Casablanca, Morocco

[4] Rockefeller Univ, Rockefeller Branch, St Giles Lab Human Genet Infect Dis, New York, NY 10021 USA

[5] Univ Paris 05, Necker Med Sch, Lab Human Genet Infect Dis, Necker Branch, Paris, France

[6] INSERM, U980, Paris, France

[7] Univ Oxford, Nuffield Dept Med, Clin Immunol Unit, Oxford, England

[8] Univ Tennessee, Coll Med, Dept Pediat, Memphis, TN 38163 USA

[9] St Jude Childrens Res Hosp, Dept Immunol, Memphis, TN 38105 USA

[10] Mt Sinai Sch Med, Dept Med & Pediat, New York, NY USA

[11] Technion Israel Inst Technol, Meyers Children Hosp, Haifa, Israel

[12] Paris Descartes Univ, Hop Necker Enfants Malad, AP HP, Pediat Hematol Immunol Unit,Necker Med Sch, Paris, France

[13] Univ Antioquia, Grp Primary Immunodeficiencies, Medellin, Colombia

[14] Childrens Hosp, Div Immunol, Boston, MA 02115 USA

[15] Karolinska Inst, Karolinska Univ Hosp Huddinge, Dept Lab Med, Div Clin Immunol, Stockholm, Sweden

[16] Natl Def Med Coll, Dept Pediat, Saitama, Japan

[17] Childrens Hosp, Manton Ctr Orphan Dis Res, Boston, MA 02115 USA

[18] Univ Washington, Dept Pediat, Seattle, WA 98195 USA

[19] Seattle Childrens Res Inst, Seattle, WA USA

[20] Univ Calif San Francisco, Dept Pediat, San Francisco, CA USA

[21] Univ Calif San Francisco, Benioff Childrens Hosp, San Francisco, CA 94143 USA

[22] Hosp Sick Children, Dept Pediat, Div Immunol & Allergy, Toronto, ON M5G 1X8, Canada

[23] Univ Toronto, Toronto, ON, Canada

[24] Univ Childrens Hosp, Div Immunol, Zurich, Switzerland

[25] Royal Childrens Hosp Melbourne, Dept Allergy & Immunol, Melbourne, Vic, Australia

[26] Murdoch Childrens Res Inst, Melbourne, Vic, Australia

[27] Univ Melbourne, Dept Paediat, Melbourne, Vic, Australia

来源：

FRONTIERS IN IMMUNOLOGY | 2011年 / 2卷

关键词：

primary immunodeficiency diseases;

D O I：

10.3389/fimmu.2011.00054

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report the updated classification of primary immunodeficiency diseases, compiled by the ad hoc Expert Committee of the International Union of Immunological Societies. As compared to the previous edition, more than 15 novel disease entities have been added in the updated version. For each disorders, the key clinical and laboratory features are provided. This updated classification is meant to help in the diagnostic approach to patients with these diseases.

引用

页数：26