Dragon Promoter Finder: recognition of vertebrate RNA polymerase II promoters

被引：65

作者：

Bajic, VB ^{[1
]}

Seah, SH ^{[1
]}

Chong, A ^{[1
]}

Zhang, GL ^{[1
]}

Koh, JLY ^{[1
]}

Brusic, V ^{[1
]}

机构：

[1] Kent Ridge Digital Labs, BIC, KRDL, Singapore 119613, Singapore

来源：

BIOINFORMATICS | 2002年 / 18卷 / 01期

关键词：

D O I：

10.1093/bioinformatics/18.1.198

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Sum: Dragon Promoter Finder (DPF) locates RNA polymerase 11 promoters in DNA sequences of vertebrates by predicting Transcription Start Site (TSS) positions. DPF's algorithm uses sensors for three functional regions (promoters, exons and introns) and an Artificial Neural Network (ANN). Results on a large and diverse evaluation set indicate that DPF exhibits a superior predicting ability for TSS location compared to three other promoter-finding programs. Availability: http://sdmc.krdl.org.sg:8080/promoter/ Contact: bajicv@krdl.org.sg.

引用

页码：198 / 199

页数：2

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